Gansons SuperGran®

The SuperGran® is Gansons most advanced granulation system, designed to overcome the limitations of conventional high shear mixer granulators. A configurable assembly of 1 to 4 uniquely profiled impeller blades creates a uniform shear environment that eliminates dead zones, prevents bimodal behaviour, and reduces granulation time by up to 90%. Available from 10L to 3,500L, the SuperGran® serves pharmaceutical, nutraceutical, food, chemical, and EV battery manufacturing.
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The SuperGran® is developed after decades-long research by Japanese technologists, adapted for modern industrial processing.
The SuperGran® efficiently addresses and resolves common challenges in large-scale granulation and mixing, ensuring:

  • Predictable scale-up
  • Batch consistency
  • Optimized process times
  • Homogeneous material behavior
  • Energy efficiency

This cutting edge-design offers a seamless scale up from 1L to 3000L lot size.

Multi-blade impeller assembly

The SuperGran® uses a configurable assembly of 1 to 4 impeller blades, each with a unique aerodynamic profile. The Upward blade drives vortex mixing, lifting material outward into the shear zone.
  • The 4-C blade ensures uniform binder distribution throughout the product mass.
  • The S-blade acts as a high-speed chopper for deagglomeration.
  • A co-axial scraper prevents wall adhesion, keeping all material in the active shear zone.
  • In EV battery applications, dedicated Dissolver blades optimise electrode slurry homogeneity.
  • The combination of blades is selected based on product properties and desired granule characteristics.

Up to 90% faster granulation

Experimentally validated reductions in process time of up to 90% compared to conventional RMG designs have been demonstrated.

  • The uniform shear environment achieves granule homogeneity faster because there are no dead zones requiring extended cycling to reach.
  • Sharp endpoint detection based on time, torque, and other configurable process variables prevents over-granulation.

Up to 90% faster granulation

Experimentally validated reductions in process time of up to 90% compared to conventional RMG designs have been demonstrated.

  • The uniform shear environment achieves granule homogeneity faster because there are no dead zones requiring extended cycling to reach.
  • Sharp endpoint detection based on time, torque, and other configurable process variables prevents over-granulation.

Eliminates bimodal behaviour

Bimodal particle size distributions are a common challenge with difficult APIs including paracetamol.

  • The SuperGran®'s uniform shear environment prevents the segregation of fine and coarse fractions throughout the granulation cycle, producing consistent unimodal distributions that improve flow, compression, and content uniformity.

Capacity and Scalability

Available from 10L laboratory scale through 3,500L commercial production, with linear, validated scalability.

  • A high turndown ratio of 20% to 100% fill in the W configuration allows flexible batch sizing within a single unit.
  • The SuperGran® can also heat or cool the substrate in-process, accommodating temperature-sensitive formulations.

Capacity and Scalability

Available from 10L laboratory scale through 3,500L commercial production, with linear, validated scalability.

  • A high turndown ratio of 20% to 100% fill in the W configuration allows flexible batch sizing within a single unit.
  • The SuperGran® can also heat or cool the substrate in-process, accommodating temperature-sensitive formulations.

Automation and Control

Gansons equipment is available with an integrated intelligent automation platform. Key features include:

  • PLC/SCADA-based control with touch-screen HMI
  • Centralised recipe management with role-based access control
  • IoT enabled for remote monitoring and pre-emptive analytics
  • Integrable with any site architecture including MES, ERP, and LIMS
  • Customised reporting and smart graphs for lot reproducibility
  • Industry-leading IPC processors for fast, reliable control performance
  • GAMP 5-aligned computerised system validation documentation supplied with 21 CFR Part 11 configurations

Capacity Range

5L – 3500L

Compliance and Certifications

Frequently asked questions

How does the SuperGran® achieve up to 90% faster granulation?

The multi-blade impeller assembly creates a uniform shear environment throughout the product mass, eliminating dead zones that force conventional granulators to extend mixing time. The co-axial scraper keeps all material in the active shear zone throughout the cycle.

Pharmaceutical granulation, nutraceutical production, food ingredient granulation, chemical manufacturing, and EV battery electrode slurry preparation.

Yes. The uniform shear environment prevents fine and coarse fraction segregation. This is particularly documented for paracetamol and similar challenging formulations.

Yes. In-process heating and cooling of the substrate is available, suitable for temperature-sensitive formulations and for processes requiring controlled thermal conditions during granulation.

Downloads

  • Brochure – Gansons SuperGran®